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Potential impact of genetic variants in Nrf2 regulated antioxidant genes and risk prediction of diabetes and associated cardiac complications

10.1016/j.jnutbio.2006.12.003 J Nutr Biochem

Specific effects depend on dose, format, individual factors, and concurrent interventions

This protective mechanism is likely linked to the prevention of lipid ROS accumulation in plasma membranes and the reduction of phospholipids containing oxidizable PUFAs, an effect that requires ACSL3 activation

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